A federal judge on Monday temporarily blocked the National Institutes of Health from cutting research funding in 22 states that filed suit earlier in the day arguing that the plan would eviscerate studies into treatments for cancer, Alzheimer’smango win, heart disease and a host of other ailments.

The funding cuts, announced late Friday, were to take effect on Monday. But the attorneys general of Massachusetts and 21 other states sued. They argued that the Trump administration’s plan to slash $4 billion in overhead costs — known as “indirect costs” — violated a 79-year-old law that governs how administrative agencies establish and administer regulations.

Overall, violent crime fell 3 percent and property crime fell 2.6 percent in 2023, with burglaries down 7.6 percent and larceny down 4.4 percent. Car thefts, though, continue to be an exception, rising more than 12 percent from the year before.

But the move backfired in a way that few supporters expected. Californians in 2021 actually tossed nearly 50 percent more plastic bags, by weight, than when the law first passed in 2014, according to data from CalRecycle, California’s recycling agency.

“Without relief from N.I.H.’s action, these institutions’ cutting-edge work to cure and treat human disease will grind to a halt,Milyon88 Official Website” the lawsuit said.

By Monday evening, the relief had been granted. Judge Angel Kelley of the U.S. District Court for the District of Massachusetts issued a temporary restraining order asking the 22 states to file a status report in 24 hours and again every two weeks to confirm the regular disbursement of the funds. The judge set a hearing for Feb. 21.

The filing is the latest in a string of lawsuits challenging President Trump’s policies. Also on Monday, a federal judge in Rhode Island ordered the Trump administration to “immediately restore” trillions of dollars in federal grants and loans, including from the N.I.H., that had been frozen under a sweeping directive the president issued, and later rescinded, late last month.

The order leaves out states that did not join the lawsuit, which will still face the funding cuts. They include some states that receive generous research awards, including Pennsylvania, which receives about $2.7 billion in N.I.H. funds, and Alabama, which receives about $500 million in agency funds. Georgia and Missouri were also not part of the lawsuit, and each draws about $1 billion in the medical study grants.

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